Indomitable in his desire to win always and everywhere, a race car "Lightning" McQueen suddenly discovers that it went astray and got stuck in a small provincial town of Radiator Springs, which is located somewhere on Route 66 in California. Participating in the race for the Piston Cup, where he was opposed by two very experienced opponents, McQueen did not expect that from now on he would have to deal with the characters of a different kind. This, for example, are Sally - a chic Porsche 2002 model year, Doc Hudson - a passenger car model "Hudson Hornet" 1951 model year, or Meter - a rusty truck-wrecker. And they all help McQueen understand that in the world there are more important things than fame, prizes and sponsors.