In the new story of the search for truth, betrayal, eternal youth and mortal danger, Captain Jack Sparrow has to meet a woman from his past, Angelica. Until the very end it is not clear whether real love unites them, or Angelica artfully pretends to get to the mysterious source of eternal youth with Jack. She forces Captain Jack Sparrow to climb aboard the ship "Queen Anne's Reveng", runned by a treacherous villain Blackbeard. Our hero finds himself in a situation where he does not know what he fears more - a terrible villain, or his old girlfriend.