Luke Watson seems like an ordinary teenager, but he carries the werewolf gene. When a government organization responsible for controlling unusual creatures discovers this, Luke and his family are relocated to Creak Street. The town is inhabited by monsters, vampires, zombies, and ghosts. There, the boy finds true friends, including a young vampire named Resus and a mummy called Cleo. Together, the heroes experience incredible adventures. Luke tries to adapt to his new reality in this strange place while protecting his loved ones.