Rushing to a crucial job interview, Chris Flynn bypasses a highway traffic jam by taking an old back road. A split-second lapse in concentration causes his car to crash into a car belonging to a group of young people. Stranded deep in the West Virginia woods with no cell service, a few of them set out to look for help. Soon, the travelers stumble upon a sinister cabin—completely unaware that they have just become targets for bloodthirsty local cannibals.