Harry and Sally know each other since the creation of the world. They studied together, came to rescue each other in any life debacles, helped in the search for a loved one. Even when they lose sight of each other, fate brings them together again and again. They have been best friends for ages. But their friendship is constantly under threat. Both are persistently tormented by the question: should they become more than friends? Can men and women really be friends? Or such friendship inevitably ends with closer relations sooner or later?