On November 14, 1974, the police station received a horrible call: in De Foe family residence six people were shot in their beds. Ronald De Foe has confessed in killing his parents and brothers, explaining that some "voices" told him to commit the murder. A year later, George and Kathy Lutz and their three children move into this house, believing that their dream have come true. They do not know that their happiness is threatened by a terrible demonic force capable of destroying it. Horror takes over Amityville again.